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Do my capstone student activities unit 6 lesson 38 capstone roofing az fsa bank complaints report I think about the people in our final story tonight every year around the time they're awarding the Nobel prizes it was 60 years ago in 1947 this st. Louis couple won the nobel prize in medicine and you can tell their story because of the importance of the work they did you can also tell it just because it's a great story the thing which which be an only child I realized was that they truly loved one another great model great thing for a child to grow up seeing people that liked one another and and had a good time together most of us are a combination of outstanding people who influenced our careers and I was very fortunate I've had a number of outstanding mentors but none could approach the quarries they were the most impressive people I've ever met there's was a true partnership a personal and scientific collaboration that had started years before in another city on another continent they had both been born into families of culture and education at the end of the old century in one of the great old cities of Europe frog which was then part of the austro-hungarian empire they both went to medical school in the city's famous University that's where Karl Corey and Gertie rabbits met and where they both decided that rather than practice medicine they wanted to do research and they wanted to do it together well my grandfather that is my mother's father toward the end of his life became diabetic and he said to his daughter who was a doctor find me a cure and that allegedly so says the family myth is why they started to work on sugar and so they were interested really in their whole life in sugar metabolism how sugar is huge in the body and then um and then any diseases that related to that by the time they graduated from medical school and got married in 1920 the old europe of their childhood had been torn apart by the Great War there were new countries and new borders economies had been laid to waste there were refugees and widespread hunger throughout Central Europe there was f Nichkhun political unrest as democracy communism and fascism battled for supremacy it was a difficult and uncertain time to start a career and plan a future although Carl was able to find a position at an Austrian university but Carl knew that gurdy who was Jewish didn't stand a chance of getting appointed indeed he was one of his mentors who he described his brilliant but anti-semitic would never give her an appointment so they decided to come to this country and never regret it they came to America in 1922 to work at a Medical Institute in Buffalo New York where they began their groundbreaking research and where they became US citizens in 1931 the Washington University School of Medicine offered them the opportunity to give even greater attention to their research actually they offered the opportunity to Karl but he made it clear that even though the university had a policy against appointing spouses they would have to find a position for Gertie as well and they did he had demanded I mean she wanted it but he was the one who really saw do you want me you're going to take my wife it was the best deal we ever made Karl Corey was once advised that it was unamerican to have his wife working with him and that it would hurt his career but this was not the case of the brilliant doctor and his assistant these were two brilliant doctors and both of them knew that they could achieve more together than they could on their own they were a remarkable pair Gertie would have flights of fancy she come up with extraordinary ideas Corey had the ability to put them into concrete questions to answer and therefore as a team they were extraordinary neither one I'm slept very much because I think when you have that kind of mind it's pretty hard to turn it off if i was born in 36 and allegedly my mom dashed over to to the maternity hospital had me and dashed back again because doing so pretty interesting work it had been known for a long time that the human body stored sugar as glycogen and then when energy was needed it broke it down into glucose to be burned as fuel without the advanced laboratory technology available today the quarries designed experiments and invented new techniques that would enable them to break down and define the complex sequence of chemical reactions they then replicated the process synthesizing glycogen in a test tube the nobel committee called that beyond doubt one of the most brilliant achievements in modern biochemistry so they isolated some of the key enzymes involved and how you use glucose and worked out the systems in which they operate that forms the basic training we give second year as a matter of fact kids learn in high school that stuff in 1947 the quarries got some news from Stockholm Sweden they had been awarded the Nobel Prize and I can remember this they got a phone call and um he was early in the morning probably at seven o'clock and the obviously whatever it happened would have excited them greatly and they were in high spirits when the news was made public the university insisted they hold a news conference that day and they told newspaper reporters they were pleased overwhelmed and too busy to celebrate the report in The Post Dispatch said they were modest and seemed in a polite way as if they'd like to be getting back to work Gertie who was the first American woman to win the Nobel Prize was described as charming but shy Gertie wouldn't tolerate anything Gertie was gracious but you knew Gertie was not to be pushed around what was it like being a woman in academia I never heard my mother complain and never heard her say anything that was negative she was just very thankful that she had this chance to do things and do things that you love and I think she was very happy to have had that they were among the greatest scientists of their generation but they were also great teachers six people who worked in their laboratory here at the washi medical school would go on to win their own Nobel prizes and that's an astonishing achievement one of those Nobel laureates later said the highest praise you could get into Cory's lab was for Gertie to call you a good worker they chose just a few young promising scientists to work in their small laboratory they welcomed input and comment they were generous and giving credit where it was due and the place was bubbling with ideas and discussions and we all sit around eating lunch and then we'd have esoteric discussions about art music politics and anybody who was famous in biochemistry would visit they were always invited to lunch so the young graduate students and the postdocs would be sitting there eating their sandwich that was an environment which was purely intellectual and stimulating the year they won the Nobel Prize gerty cori was diagnosed with a rare disease and this woman who had always loved the outdoors loved hiking in the mountains of Europe and America would grow progressively weaker over the coming years but the commitment and devotion the couple had forged years before was there till the end and at one point she got so weak she had trouble walking down the Carter and you'd hear her yell out Carly he get up walk down and pick her up and walk her back to the for lunch I mean it was an extraordinary pair and it had its effect on everybody that was working there Gertie radnet skory died in 1957 Carl Corey later moved to Harvard where he continued to do research until his death in 1980 they had made major discoveries which have been put to use in countless ways that will live on less obvious and perhaps soon to be forgotten altogether are the contributions they made as teachers and mentors of the next generation of scientists the next generation of medical discoveries these were the partners behind the prize capstone ski centre postcode order Culinary Institute of America.